Why and how do we classify von Willebrand disease?
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چکیده
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Recent multicenter studies have clarified the molecular basis underlying the different von Willebrand disease (VWD) types, all of which are caused by the deficiency and/or abnormality of von Willebrand factor (VWF). These studies have suggested a unifying pathophysiologic concept. The diagnosis of VWD, remains difficult because its clinical and laboratory phenotype is very heterogeneous and may...
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ژورنال
عنوان ژورنال: Haemophilia
سال: 2015
ISSN: 1351-8216
DOI: 10.1111/hae.12725